Modelling Brain Cancer

Human Patient Samples

 

Cells isolated from small patient biopsies provide us with an excellent biological model for testing our oncolytic viruses.

 

By comparing healthy and cancer cells isolated from the same patient, we can determine if an oncolytic therapy can accurately distinguish between the two. This is an important safety feature for any anti-cancer therapy.

 

We can grow the patient's cells not only in flat monolayers, but also in 3-D "neurospheres" that accurately depict the brain in its natural state (see images above).

 

Images above courtesy of our collaborator, Dr. Lorimer.

neurospheres monolayer, brain, cancer neurospheres three dimensional brain cancer