Cancer at its most basic is the corruption of normal biological programs that control cell proliferation, metabolism, death, motility, stickiness and immune functions.
Our lab harnesses the natural world of viruses to fight cancer. We design and develop programmable replicating viruses called “oncolytic viruses” as biotherapies that directly target cancer cells and activate a patient's own immune system against their tumour.
We focus on the treatment of childhood cancers, and are based at the Children's Hospital of Eastern Ontario Research Institute in Ottawa, Canada.
Our Maraba-MG1 oncolytic virus is currently in clinical trials across Canada. Our Farmington virus vaccine is scheduled to start clinical trials in brain cancer patients in Fall 2018. Find out more here.